SS-31

SS-31 (Elamipretide) 10 mg



SS-31 (Elamipretide) is a mitochondria-targeting peptide designed to support mitochondrial function, cellular energy production, and protection against oxidative stress. It selectively binds to cardiolipin within the inner mitochondrial membrane, helping maintain efficient energy production and mitochondrial integrity.



Potential Benefits



Mitochondrial Health



* Supports healthy mitochondrial function

* Helps maintain cellular energy (ATP) production

* Protects mitochondrial membranes

* Promotes efficient cellular metabolism



Energy & Physical Performance



* May reduce fatigue

* Supports exercise endurance

* Enhances cellular energy availability

* May improve recovery after physical activity



Muscle Recovery



* Supports muscle cell function

* May reduce oxidative stress associated with intense exercise

* Promotes recovery and tissue resilience



Cardiovascular Support



* Supports healthy heart cell mitochondria

* Investigated for improving cardiac energy metabolism

* May help protect cardiac tissue from oxidative damage



Neuroprotection



* May support healthy neuronal function

* Investigated for neurodegenerative conditions

* Helps reduce mitochondrial oxidative stress in nerve cells



Mechanism of Action



SS-31 works by:



* Binding to cardiolipin, a phospholipid unique to the inner mitochondrial membrane

* Supporting efficient electron transport chain function

* Reducing excessive reactive oxygen species (ROS)

* Improving ATP production

* Helping preserve mitochondrial structure during cellular stress



Suggested Administration



SS-31 is generally administered by subcutaneous (SC) injection in research settings. There is no FDA-approved dosing regimen for general clinical use.



Storage



* Store lyophilized peptide refrigerated (2–8°C / 36–46°F)

* After reconstitution, refrigerate

* Protect from light

* Avoid repeated freeze-thaw cycles



Possible Side Effects



Human safety data remain limited. Reported or potential side effects include:



* Injection site irritation

* Mild headache

* Nausea

* Temporary fatigue

* Flushing (uncommon)



Research Areas



SS-31 is being investigated for:



* Mitochondrial diseases

* Heart failure

* Age-related muscle loss

* Kidney disease

* Neurodegenerative disorders

* Exercise recovery

* Healthy aging



Notes



* SS-31 is an investigational mitochondrial peptide and is not FDA-approved for routine clinical use.

* Most evidence comes from clinical research and experimental studies, with ongoing trials evaluating its safety and effectiveness.

* Its proposed benefits center on mitochondrial protection and cellular energy support, rather than direct muscle growth or weight loss.